Below are the list of Ministries established for 2025-2028 Civil Service administration under the Civil Service Act 1993 (P.N.D.C.L. 327) section 11(33). Established under Civil Service (Ministries) Instrument, 2025 by H.E John Dramani Mahama.
- Ministry of Finance
- Ministry of Health
- Ministry of Interior
- Ministry of Defense
- Ministry of Education
- Ministry of Energy and Green Transition
- Ministry of Roads and Highway
- Ministry of Transport
- Ministry of Sports and Recreation
- Office of the Attorney-General and Ministry of Justice
- Ministry of Lands and Natural Resources
- Ministry of Local Government Chieftaincy, and Religious Affairs
- Ministry of Foreign Affairs
- Ministry of Communication, Digital Technology, and Innovations
- Ministry of Environment, Science and Technology
- Ministry of Youth Development and Empowerment
- Ministry of Works, Housing and Water Resources
- Ministry of Gender, Children and Social Protection
- Ministry of Tourism, Culture, and Creative Arts
- Ministry of Labour, Jobs, and Employment
- Ministry of Food and Agriculture
- Ministry of Fisheries and Aquaculture
- Ministry of Trade, Agribusiness, and Industry
This revokes the Civil Service (Ministries) Instrument, 2021 (E.I 12).